Nicotine Content Matters: What an Independent Lab Study Reveals About Oral Pouches and Smokeless Tobacco Substitution

A new, independently conducted clinical study in Experimental and Clinical Psychopharmacology offers rare, high-quality evidence on how oral nicotine pouches perform for people who already use smokeless tobacco (SLT) and why nicotine content is the hinge on which substitution success turns. What the study asked and why it matters Alisha Eversole and colleagues at Virginia…

Restricting Nicotine Pouches Makes Quitting Harder for Workers

Policies meant to restrict access to nicotine pouches are turning out to be counterproductive, especially for workers, whose access to tobacco alternatives is already constrained by time, location, and economic pressures. In New Brunswick, Canada, a construction worker’s story powerfully illustrates the human cost when safer options are forced off convenience shelves and buried behind…

The Next Evolution of Oral Pouches: From Harm Reduction to Wellness and Beyond

At the New Approaches Summit 2025, the conversation around oral pouches moved beyond nicotine. What began as a harm reduction innovation has now evolved into a platform with potential far beyond smoking alternatives. Oral pouches, once defined by snus and nicotine, are being reimagined as discreet, fast-acting vehicles for functional microdosing and even emerging therapeutic…

FDA Moves to Fast-Track Nicotine Pouch Reviews Under White House Pressure

The U.S. Food and Drug Administration (FDA) is accelerating its review of nicotine pouches, responding to mounting pressure from the White House to clarify the regulatory status of one of the fastest-growing categories in tobacco harm reduction. A Rapidly Expanding Market in Limbo Nicotine pouches, tobacco-free oral sachets delivering nicotine without combustion, have surged in…