Smoke-Free Products and Harm Reduction: What the Toxicology Tells Us

Despite decades of progress in tobacco control, smoking remains widespread across Europe. In countries like Germany, millions continue to smoke with little motivation to quit, leaving policymakers and scientists searching for pragmatic ways to reduce the toll of combustible tobacco. A recent article in Internal and Emergency Medicine by aerosol chemist Reinhard Niessner brings the…

Toward Smarter Tobacco Regulation: Lessons from Global Approaches

Around the world, governments are rethinking how best to regulate tobacco and nicotine products in light of new science and innovation. Traditional tobacco control has long focused on restrictions and prohibitions, but the emergence of smoke-free alternatives, such as heated tobacco, e-cigarettes, and oral nicotine pouches, demands a more nuanced, evidence-based approach. The Need for…

Rethinking Nicotine: Modulation, Mood, and Neuroprotection via nAChRs

Despite decades of stigma, nicotine continues to reveal surprising roles in brain health through its interaction with nicotinic acetylcholine receptors (nAChRs). From improving attention to potentially slowing neurodegeneration, new science challenges outdated assumptions—and calls for a more nuanced conversation. Cognition and Mood: Nicotine’s Modulatory Role Nicotine’s primary mechanism of action in the brain is through…

Oral Nicotine Use: A Global Perspective on Regional Traditions and Regulation

From the betel-stained smiles of Southeast Asia to Scandinavia’s sleek pouch packaging, the rise of oral nicotine is not a one-size-fits-all story. Regional traditions, risk perceptions, and regulatory choices are shaping the path of harm reduction around the world, highlighting both promise and pitfalls. Southeast Asia: Tradition Meets Resistance Southeast Asia is home to more…

Kenya at a Crossroads: Regulating Nicotine Pouches and the Future of Tobacco Harm Reduction

By Joseph Magero Kenya is on the brink of a pivotal decision in its tobacco control journey. The Tobacco Control (Amendment) Bill 2024, now under review by the Senate, is poised to introduce long-overdue regulation of new nicotine products, specifically nicotine pouches, e-cigarettes, and other smokeless alternatives that have until now existed in legal limbo.…

The Cultural Tapestry of Tobacco in India: Tradition, Inequality & Control

India’s tobacco landscape is uniquely complex and deeply rooted in social, regional, and cultural practices. This narrative review examines how tradition, yes, but also inequality and economic factors, shape tobacco use, and what that means for policy. Deep Roots: Tobacco as Tradition and Livelihood Tobacco in India isn’t new, it’s woven into rituals, social ceremonies,…