Rethinking Nicotine: Modulation, Mood, and Neuroprotection via nAChRs

Despite decades of stigma, nicotine continues to reveal surprising roles in brain health through its interaction with nicotinic acetylcholine receptors (nAChRs). From improving attention to potentially slowing neurodegeneration, new science challenges outdated assumptions—and calls for a more nuanced conversation. Cognition and Mood: Nicotine’s Modulatory Role Nicotine’s primary mechanism of action in the brain is through…